Abstract: A summary of the latest results on the evidence of the four-top-quark production using proton-proton collision data at a centre of-mass energy of 13 TeV collected by the ATLAS detector at the Large Hadron Collider with an integrated luminosity of 139 fb−1. Events are selected if they contain a same-sign lepton (electron or a muon) pair or at least three leptons (2lSS/3l) or a single lepton or an opposite-sign lepton pair (1l/2lOS). A multivariate technique is used to discriminate between signal and background events in the signal rich regions. The combined four top-quark production cross section is measured to be 24 +7/−6 fb, with a corresponding observed (expected) signal significance of 4.7 (2.6) standard deviations over the background-only predictions. It is consistent within 2.0 standard deviations with the Standard Model expectation of 12.0 ± 2.4 fb.